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\u672c\u6b21\u4e0a\u5e02\u7533\u8bf7\u7684\u6279\u51c6\u4e3b\u8981\u57fa\u4e8eJUPITER-02\uff08\u4e00\u9879\u9488\u5bf9\u4e00\u7ebf\u6cbb\u7597\u9f3b\u54bd\u764c\u7684\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u56fd\u9645\u591a\u4e2d\u5fc3\u2162\u671f\u4e34\u5e8a\u7814\u7a76\uff0cNCT03581786\uff09\u53caPOLARIS-02\uff08\u4e00\u9879\u9488\u5bf9\u4e8c\u7ebf\u53ca\u4ee5\u4e0a\u6cbb\u7597\u7684\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001\u2161\u671f\u5173\u952e\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\uff0cNCT02915432\uff09\u7684\u7814\u7a76\u7ed3\u679c\u3002<\/p>\n\n\n\n

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POLARIS-02\u7814\u7a76\u7ed3\u679c\u5df2\u4e8e2021\u5e741\u6708\u5728\u7ebf\u53d1\u8868\u4e8e\u300a\u4e34\u5e8a\u80bf\u7624\u5b66\u6742\u5fd7\u300b\uff08Journal of Clinical Oncology<\/em>\uff0c\u5f71\u54cd\u56e0\u5b50\uff1a42.1\uff09\u3002\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5728\u65e2\u5f80\u5316\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u4e2d\u8868\u73b0\u51fa\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u53ef\u63a7\u7684\u5b89\u5168\u6027\uff0c\u60a3\u8005ORR\u4e3a20.5%\uff0cDoR\u4e3a12.8\u4e2a\u6708\uff0c\u4e2d\u4f4dOS\u8fbe17.4\u4e2a\u6708\u3002<\/p>\n\n\n\n

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1. <\/em>\u672c\u6750\u6599\u65e8\u5728\u4f20\u9012\u524d\u6cbf\u4fe1\u606f\uff0c\u65e0\u610f\u5411\u60a8\u505a\u4efb\u4f55\u4ea7\u54c1\u7684\u63a8\u5e7f\uff0c\u4e0d\u4f5c\u4e3a\u4e34\u5e8a\u7528\u836f\u6307\u5bfc\u3002<\/em><\/h6>\n\n\n\n
2. <\/em>\u82e5\u60a8\u60f3\u4e86\u89e3\u5177\u4f53\u75be\u75c5\u8bca\u7597\u4fe1\u606f\uff0c\u8bf7\u9075\u4ece\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u7684\u610f\u89c1\u4e0e\u6307\u5bfc\u3002<\/em><\/h6>\n\n\n\n

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\u3010\u53c2\u8003\u6587\u732e\u3011<\/h5>\n\n\n\n
1. https:\/\/gco.iarc.who.int\/media\/globocan\/factsheets\/cancers\/4-nasopharynx-fact-sheet.pdf.<\/h5>\n\n\n\n
2. 2025NCCN \u4e34\u5e8a\u5b9e\u8df5\u6307\u5357\uff1a\u5934\u9888\u90e8\u80bf\u7624\uff082025.V1\uff09.<\/h5>\n\n\n\n

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\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca\u00ae<\/sup>\uff09\u4f5c\u4e3a\u6211\u56fd\u6279\u51c6\u4e0a\u5e02\u7684\u9996\u4e2a\u56fd\u4ea7\u4ee5PD-1\u4e3a\u9776\u70b9\u7684\u5355\u6297\u836f\u7269\uff0c\u83b7\u5f97\u56fd\u5bb6\u79d1\u6280\u91cd\u5927\u4e13\u9879\u9879\u76ee\u652f\u6301\uff0c\u5e76\u8363\u81ba\u56fd\u5bb6\u4e13\u5229\u9886\u57df\u6700\u9ad8\u5956\u9879\u201c\u4e2d\u56fd\u4e13\u5229\u91d1\u5956\u201d\u3002<\/p>\n\n\n\n

\u7279\u745e\u666e\u5229\u5355\u6297\u81f3\u4eca\u5df2\u5728\u5168\u7403\uff08\u5305\u62ec\u4e2d\u56fd\u3001\u7f8e\u56fd\u3001\u6b27\u6d32\u53ca\u4e1c\u5357\u4e9a\u7b49\u5730\uff09\u5f00\u5c55\u4e86\u8986\u76d6\u8d85\u8fc715\u4e2a\u9002\u5e94\u75c7\u768440\u591a\u9879\u7531\u516c\u53f8\u53d1\u8d77\u7684\u4e34\u5e8a\u7814\u7a76\u3002\u6b63\u5728\u8fdb\u884c\u6216\u5df2\u5b8c\u6210\u7684\u5173\u952e\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\u5728\u591a\u4e2a\u7624\u79cd\u8303\u56f4\u5185\u8bc4\u4f30\u7279\u745e\u666e\u5229\u5355\u6297\u7684\u5b89\u5168\u6027\u53ca\u7597\u6548\uff0c\u5305\u62ec\u80ba\u764c\u3001\u9f3b\u54bd\u764c\u3001\u98df\u7ba1\u764c\u3001\u80c3\u764c\u3001\u8180\u80f1\u764c\u3001\u4e73\u817a\u764c\u3001\u809d\u764c\u3001\u80be\u764c\u53ca\u76ae\u80a4\u764c\u7b49\u3002<\/p>\n\n\n\n

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